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货号： bs-16416R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16416R
- 英文名称
- ZNHIT3
- 中文名称
- ZNHIT3蛋白抗体
- 别 名
- HNF 4a coactivator; Thyroid hormone receptor interactor 3; Thyroid receptor interacting protein 3; TR interacting protein 3; TRIP 3; ZNHI3_HUMAN; TRIP3; Zinc finger HIT domain containing protein 3; Zinc finger HIT type 3; Zinc finger, HIT domain containing 3; Zinc finger, HIT type containing 3.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNHIT3:51-153/153
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
- PubMed
- PubMed
- 产品介绍
- background:
ZNHIT3 is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR?mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4? and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Function:
ZNHIT3 functions as a transcriptional coactivator and contains 1 HIT type zinc finger.
Subunit:
Thyroid receptor interacting proteins (TRIPs) specifically interact with the ligand binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction.
Similarity:
Contains 1 HIT-type zinc finger.
SWISS:
Q15649
Gene ID:
9326
Database links:Entrez Gene: 9326Human
Omim: 604500Human
SwissProt: Q15649Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.