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货号： bs-16391R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16391R
- 英文名称
- ZXDC
- 中文名称
- 锌指蛋白ZXDC抗体
- 别 名
- SERH2790; UNQ2790; Zinc finger protein ZXDC; ZXD family zinc finger C; ZXD like zinc finger protein; ZXD-like zinc finger protein; Zxdc; ZXDC_HUMAN; ZXDL.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 89kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZXDC:201-300/858
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Zinc finger X-linked duplicated family member C (ZXDC) is an 858 amino acid protein belonging to the ZDX family. Localized to the nucleus, ZDXC is expressed at high levels in heart, kidney, liver and testis, with lower levels of expression in lung, muscle, placenta, small intestine and spleen. ZDXC, with ZDXA, forms a complex that binds to the class II trans-activator (CIITA). CIITA, like the X1-binding regulatory factor X (RFX) complex and the nuclear factor Y (NFY) complex, is a transcriptional co-factor that is necessary, but not sufficient, for major histocompatibility complex (MHC) class II gene transcription. ZXDC, by regulating CIITA function, activates the transcription of MHC genes.
Function:
Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen.
Similarity:
Belongs to the ZXD family.
Contains 10 C2H2-type zinc fingers.
SWISS:
Q2QGD7
Gene ID:
79364
Database links:Entrez Gene: 79364Human
Entrez Gene: 80292Mouse
Entrez Gene: 362399Rat
SwissProt: Q2QGD7Human
SwissProt: Q8C8V1Mouse
Unigene: 440049Human
Unigene: 711046Human
Unigene: 100116Mouse
Unigene: 473652Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.