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货号： bs-16375R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-16375R
- 英文名称
- GW182
- 中文名称
- GW182蛋白抗体
- 别 名
- CAG repeat protein 26; CAGH26; DKFZp666E117; EDIE; EMSY interactor protein; FLJ22043; Glycine tryptophan protein of 182 kDa; Glycine-tryptophan protein of 182 kDa; GW1; GW182; GW182 autoantigen; Hypothetical protein DKFZp566M143; KIAA1460; MGC75384; OTTHUMP00000122485; OTTHUMP00000195164; OTTHUMP00000195165; Protein GW1; TNR6A_HUMAN; TNRC 6A; TNRC6; TNRC6A; Trinucleotide repeat containing 6; Trinucleotide repeat containing 6A; Trinucleotide repeat containing gene 6A protein; Trinucleotide repeat-containing gene 6A protein.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 210kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GW182:631-730/1962
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]
Function:
Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins.
Subcellular Location:
Cytoplasm > P-body. Mammalian P-bodies are also known as GW bodies.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the GW182 family.
Contains 1 RRM (RNA recognition motif) domain.
SWISS:
Q8NDV7
Gene ID:
27327
Database links:Entrez Gene: 27327Human
Entrez Gene: 233833Mouse
Entrez Gene: 308971Rat
Omim: 610739Human
SwissProt: Q8NDV7Human
SwissProt: Q3UHK8Mouse
Unigene: 407740Human
Unigene: 655057Human
Unigene: 102305Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.