产品中心
当前位置：首页>产品中心Anti-LIP5
货号： bs-4703R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-4703R
- 英文名称
- LIP5
- 中文名称
- LIP5抗体
- 别 名
- C6orf55Chromosome 6 open reading frame 55; Dopamine responsive protein DRG 1; Dopamine-responsive gene 1 protein; DRG 1; DRG-1; DRG1; Homolog of mouse SKD1 binding protein 1; HSPC228; LIP5; LYST interacting protein 5; LYST-interacting protein 5; My012; SBP1; SKD1 binding protein 1; SKD1-binding protein 1; Vacuolar protein sorting-associated protein VTA1 homolog; Vps20 associated 1 homolog (S. cerevisiae); VTA1; VTA1_HUMAN
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 微生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LIP5:101-200/307
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]
Function:
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding.
Subunit:
Interacts with VPS4B. Interacts with CHMP1B. Interacts with CHMP2A; the interaction probably involves the open conformation of (polymerized) CHMP2A. Interacts with CHMP3. Interacts with CHMP5; the interaction involves soluble CHMP5. Interacts with IST1.
Subcellular Location:
Cytoplasm. Endosome membrane; Peripheral membrane protein (Probable).
Similarity:
Belongs to the VTA1 family.
SWISS:
Q9NP79
Gene ID:
51534
Database links:Entrez Gene: 506430 Cow
Entrez Gene: 51534 Human
Entrez Gene: 66201 Mouse
Entrez Gene: 292640 Rat
GenBank: BC005937 Human
Omim: 610902 Human
SwissProt: Q32L63 Cow
SwissProt: Q9NP79 Human
SwissProt: Q9CR26 Mouse
Unigene: 431367 Human
Unigene: 227983 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.