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货号： bs-4428R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4428R-Cy3
- 英文名称
- Anti-PTPLA/Cy3
- 中文名称
- Cy3标记的蛋白酪氨酸磷酸酶PTPLA抗体
- 别 名
- 3-hydroxyacyl-CoA dehydratase 1; CAP; Cementum attachment protein; HACD1; HACD1_HUMAN; Protein-tyrosine phosphatase-like member A; PTPLA; RP23-334M9.1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PTPLA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation. [provided by RefSeq, Jul 2008]
Function:
Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Highly expressed in the myocardium, and to a lesser extent in skeletal and smooth muscular tissues including those from stomach, jejunum, and bladder.
Similarity:
Belongs to the very long-chain fatty acids dehydratase HACD family.
Database links:Entrez Gene: 9200 Human
Entrez Gene: 30963 Mouse
Omim: 610467 Human
SwissProt: B0YJ81 Human
SwissProt:Q9QY80 Mouse
Unigene:114062 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.