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货号： bs-7186R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7186R-Cy3
- 英文名称
- Anti-ZNF224/Cy3
- 中文名称
- Cy3标记的锌指蛋白224抗体
- 别 名
- BMZF 2; BMZF-2; BMZF2; Bone marrow zinc finger 2; KOX22; Zinc finger 2, bone marrow; Zinc finger protein 224; Zinc finger protein 233; Zinc finger protein 255; Zinc finger protein 27 (KOX 22); Zinc finger protein 27; Zinc finger protein KOX22; Zinc finger protein ZNF255; ZN224_HUMAN; ZNF224; ZNF255; ZNF27.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 82kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF224
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
Subunit:
Interacts with WT1. Interacts with DEPDC1A.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous. Mainly expressed in fetal tissues.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 18 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Database links:Entrez Gene: 7767Human
Omim: 194555Human
SwissProt: Q9NZL3Human
Unigene: 585869Human
Unigene: 744152Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.