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货号： bs-12633R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12633R-Cy3
- 英文名称
- Anti-SMCR7/Cy3
- 中文名称
- Cy3标记的SMCR7蛋白抗体
- 别 名
- MGC23130; MID49; MIEF2; Mitochondrial dynamic protein MID49; Mitochondrial dynamic protein of 49 kDa; Mitochondrial elongation factor 2; Smith Magenis syndrome chromosome region candidate 7; Smith-Magenis syndrome chromosomal region candidate gene 7 protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 发育生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 49kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SMCR7
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Function:
Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity.
Subcellular Location:
Mitochondrion outer membrane; Single-pass membrane protein. Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria.
Tissue Specificity:
Expressed in all tissues tested with highest expression in heart and skeletal muscle.
Similarity:
Belongs to the MID49/MID51 family.
Database links:Entrez Gene: 125170Human
Entrez Gene: 497916Rat
SwissProt: Q96C03Human
Unigene: 655555Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.