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货号： bs-21023R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21023R-Cy3
- 英文名称
- Anti-SLC6A14/Cy3
- 中文名称
- Cy3标记的碳酸氢钠协同转运蛋白6-A14抗体
- 别 名
- Amino acid transporter ATB0+; Amino acid transporter B0+; ATB0+; BMIQ11; OBX; Sodium and chloride dependent neutral and basic amino acid transporter B(0+); Sodium and chloride dependent neutral and basic amino acid transporter B0+; Solute carrier family 6 (amino acid transporter), member 14; Solute carrier family 6 (neurotransmitter transporter), member 14; Solute carrier family 6 amino acid transporter member 14; Solute carrier family 6 member 14; Solute carrier family 6 neurotransmitter transporter member 14.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 72kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC6A14
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene may be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010]
Function:
Mediates the uptake of a broad range of neutral and cationic amino acids (with the exception of proline) in a Na+/Cl--dependent manner.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Levels are highest in adult and fetal lung, in trachea and salivary gland. Lower levels detected in mammary gland, stomach and pituitary gland, and very low levels in colon, uterus, prostate and testis.
DISEASE:
Genetic variations in SLC6A14 may be associated with obesity in some populations, as shown by significant differences in allele frequencies between obese and non-obese individuals.
Similarity:
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A14 subfamily.
Database links:Entrez Gene: 11254Human
Entrez Gene: 56774Mouse
Entrez Gene: 298340Rat
Omim: 300444Human
SwissProt: Q9UN76Human
SwissProt: Q9JMA9Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.