产品中心
当前位置：首页>产品中心Anti-FAM125A
货号： bs-14713R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14713R
- 英文名称
- FAM125A
- 中文名称
- FAM125A蛋白抗体
- 别 名
- CFBP; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; F125A_HUMAN; FAM125A; Family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 细胞定位
- 细胞核 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FAM125A:131-230/273
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor.
Subcellular Location:
Cytoplasm. Nucleus. Endosome. Cytoplasm > cytoskeleton > centrosome. Late endosome membrane. Colocalizes with F-actin. Some fraction may be nuclear.
Tissue Specificity:
Ubiquitously expressed except in skeletal muscle.
Post-translational modifications:
Phosphorylated on Tyr-204 upon EGF stimulation. Phosphorylation is required for interaction with CD2AP and CIN85/SH3KBP1.
Similarity:
Belongs to the FAM125 family.
Contains 1 MABP domain.
Contains 1 UMA domain.
SWISS:
Q96EY5
Gene ID:
93343
Database links:Entrez Gene: 93343Human
SwissProt: Q96EY5Human
Unigene: 515243Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.