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货号： bs-14659R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14659R
- 英文名称
- EXOC2
- 中文名称
- EXOC2蛋白抗体
- 别 名
- EX3L1_HUMAN; Exoc3l1; Exocyst complex component 3-like protein; FLJ35539; FLJ35587; Protein Jiangli
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 神经生物学 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 82kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EXOC2:1-100/746
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
ExoC3L is a 746 amino acid protein that belongs to the SEC6 family. Localizing to the cytoplasmic and secretory vesicle, ExoC3L colocalizes with insulin granules and interacts with ExoC2, ExoC4 and ExoC5. Acting as part of the exocyst, ExoC3L may function in the regulation of insulin granule exocytosis and is expressed in insulin-secreting MIN6 cells, as well as various tissues including brain and pancreatic islets. The gene encoding ExoC3L maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohns disease, which is a gastrointestinal inflammatory condition.
Function:
As part of the exocyst, may play a role in regulated exocytosis of insulin granules.
Subcellular Location:
Cytoplasmic vesicle； secretory vesicle. Colocalizes with insulin granules.
Similarity:
Belongs to the SEC6 family.
SWISS:
Q86VI1
Gene ID:
283849
Database links:Entrez Gene: 283849Human
Omim: 614117Human
SwissProt: Q86VI1Human
Unigene: 647356Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.