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货号： bs-19325R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19325R-Cy3
- 英文名称
- Anti-NPAS4/Cy3
- 中文名称
- Cy3标记的神经细胞PAS结构域蛋白4抗体
- 别 名
- bHLH PAS type transcription factor NXF;bHLHe79;bHLHe79;Class E basic helix-loop-helix protein 79;HLH-PAS transcription factor NXF;Le PAS;limbic enhanced PAS protein;neuronal PAS domain protein 4;Neuronal PAS domain-containing protein 4;Neuronal PAS4;NPAS4;NPAS4_HUMAN;NXF;PAS domain-containing protein 10;PASD10.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 87kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NPAS4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008]
Function:
Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.
Subunit:
Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with ARNT.
Subcellular Location:
Nucleus.
Tissue Specificity:
Brain.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 2 PAS (PER-ARNT-SIM) domains.
Database links:Entrez Gene: 266743Human
Entrez Gene: 225872Mouse
Entrez Gene: 266734Rat
Entrez Gene: 724016Zebrafish
Omim: 608554Human
SwissProt: Q8IUM7Human
SwissProt: Q8BGD7Mouse
SwissProt: Q8CJH6Rat
SwissProt: Q1ECW2Zebrafish
Unigene: 256036Human
Unigene: 287867Mouse
Unigene: 86654Rat
Unigene: 81110Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.