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货号: bs-19300R-Cy3 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-19300R-Cy3
- 英文名称
- Anti-NNMT/Cy3
- 中文名称
- Cy3标记的烟酰胺N-甲基转移酶抗体
- 别 名
- EC 2.1.1.1; Nicotinamide N methyltransferase; Nicotinamide N-methyltransferase; NNMT; NNMT_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NNMT
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor. [provided by RefSeq, Jul 2008]
Function:
Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
Subunit:
Monomer.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas.
Similarity:
Belongs to the NNMT/PNMT/TEMT family.
Database links:Entrez Gene: 4837Human
Entrez Gene: 18113Mouse
Entrez Gene: 100144485Pig
Entrez Gene: 300691Rat
Omim: 600008Human
SwissProt: P40261Human
SwissProt: O55239Mouse
SwissProt: Q06AV1Pig
Unigene: 503911Human
Unigene: 623245Human
Unigene: 458542Mouse
Unigene: 8362Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.