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货号： bs-19286R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19286R-Cy3
- 英文名称
- Anti-NLRP14/Cy3
- 中文名称
- Cy3标记的NLRP14蛋白抗体
- 别 名
- CLR11.2; GC-LRR; LRR and PYD domains-containing protein 14; NACHT; NACHT, leucine rich repeat and PYD containing 14; NACHT, LRR and PYD containing protein 14; NACHT, LRR and PYD domains-containing protein 14; NAL14_HUMAN; Nalp-iota; NALP14; NLR family, pyrin domain containing 14; NLRP14; NOD5; Nucleotide-binding oligomerization domain protein 5; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14; PAN8.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞凋亡 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 125kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NLRP14
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
Function:
May be involved in inflammation and spermatogenesis.
Tissue Specificity:
Testis-specific.
DISEASE:
In the testis, expressed mainly in A dark spermatogonia, mid and late spermatocytes and spermatids but not in mitotically active A pale and B spermatogonia.
Similarity:
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 11 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Database links:Entrez Gene: 338323Human
Omim: 609665Human
SwissProt: Q86W24Human
SwissProt: Q6B966Mouse
Unigene: 449637Human
Unigene: 618600Human
Unigene: 35644Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.