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货号： bs-19246R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19246R-Cy3
- 英文名称
- Anti-NIF1/Cy3
- 中文名称
- Cy3标记的锌指蛋白335抗体
- 别 名
- 1810045J01Rik; bA465L10.2; FZF-1; MGC86001; NIF-1; NIF-2; NIF2; NIF2, INCLUDED; NRC interacting factor 1; NRC-interacting factor 1; NRC-INTERACTING FACTOR; Nuclear Receptor Coactivator Interacting Factor 1; OTTHUMP00000031195; Zinc finger protein 335; Zinc finger/leucine zipper co transducer NIF1; zinc-finger/leucine-zipper co-transducer NIF1; ZNF335.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 145kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NIF1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene enhances transcriptional activation by ligand-bound nuclear hormone receptors. However, it does this not by direct interaction with the receptor, but by direct interaction with the nuclear hormone receptor transcriptional coactivator NRC. The encoded protein may function by altering local chromatin structure. [provided by RefSeq, Jul 2008]
Function:
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells (By similarity). Preferentially catalyzes the dephosphorylation of Ser-5 within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation.
Subcellular Location:
Nuclear
Tissue Specificity:
Expression is restricted to non-neuronal tissues.
Database links:Entrez Gene: 535476Cow
Entrez Gene: 485904Dog
Entrez Gene: 63925Human
Omim: 610827Human
SwissProt: Q9H4Z2Human
Unigene: 174193Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.