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货号： bs-20214R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20214R-Cy3
- 英文名称
- Anti-RAMP1/Cy3
- 中文名称
- Cy3标记的受体活性修饰蛋白1抗体
- 别 名
- calcitonin receptor like receptor activity modifying protein 1; RAMP 1; RAMP-1; CRLR activity modifying protein 1; receptor (G protein coupled) activity modifying protein 1; receptor activity modifying protein 1; Receptor activity modifying protein 1; RAMP1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞膜受体 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 14kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a member of the RAMP family of single transmembrane domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin receptor like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Function:
Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.
Subunit:
Heterodimer of CALCRL and RAMP1.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.
Similarity:
Belongs to the RAMP family.
Database links:Entrez Gene: 10267 Human
Entrez Gene: 51801 Mouse
Entrez Gene: 58965 Rat
Omim: 605153 Human
SwissProt: O60894 Human
SwissProt: Q9WTJ5 Mouse
SwissProt: Q9JJ74 Rat
Unigene: 471783 Human
Unigene: 3272 Mouse
Unigene: 12265 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.