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货号: bs-14597R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-14597R
- 英文名称
- ENOX1
- 中文名称
- ENOX1蛋白抗体
- 别 名
- bA64J21.1; Candidate growth related and time keeping constitutive hydroquinone [NADH] oxidase; Candidate growth-related and time keeping constitutive hydroquinone [NADH] oxidase; cCNOX; Cell proliferation inducing gene 38 protein; Cell proliferation-inducing gene 38 protein; cNOX; Constitutive Ecto NOX; Constitutive Ecto-NOX; Ecto NOX disulfide thiol exchanger 1; ENOX1; ENOX1_HUMAN; FLJ10094; OTTHUMP00000018332; PIG38; Proliferation inducing protein 38; Protein disulfide-thiol oxidoreductase.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 73kDa
- 细胞定位
- 细胞浆 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ENOX1:541-643/643
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene is a tumor-specific member of the ECTO-NOX family of genes that encode cell surface NADH oxidases. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The protein also displays prion-like properties. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Function:
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol interchange/oxidoreductase activity which may control physical membrane displacements associated with vesicle budding or cell enlargement. The activities oscillate with a period length of 24 minutes and play a role in control of the ultradian cellular biological clock.
Subcellular Location:
Cell membrane. Secreted; extracellular space. Extracellular and plasma membrane-associated.
Tissue Specificity:
Expressed in lymphocyte cells, breast and breast cancer (at protein level). Found in the sera of cancer patients with a wide variety of cancers including breast, prostate, lung and ovarian cancers, leukemias, and lymphomas. Found also in the serum of healthy volunteers or patients with disorders other than cancer. Probably shed into serum by cancer cells.
Similarity:
Belongs to the ENOX family.
Contains 1 RRM (RNA recognition motif) domain.
SWISS:
Q8TC92
Gene ID:
55068
Database links:Entrez Gene: 10495Human
Entrez Gene: 55068Human
Entrez Gene: 209224Mouse
Entrez Gene: 239188Mouse
Entrez Gene: 306038Rat
Omim: 610914Human
SwissProt: Q16206Human
SwissProt: Q8TC92Human
SwissProt: Q8BHR2Mouse
SwissProt: Q8R0Z2Mouse
Unigene: 128258Human
Unigene: 171458Human
Unigene: 327730Mouse
Unigene: 441158Mouse
Unigene: 490096Mouse
Unigene: 212211Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.