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货号： bs-14594R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14594R
- 英文名称
- FXNA
- 中文名称
- 内质网金属肽1抗体
- 别 名
- Endoplasmic reticulum metallopeptidase 1 aminopeptidase Fxna; bA207C16.3 (novel protein similar to predicted yeast, plant and worm proteins); bA207C16.3; Endoplasmic reticulum metallopeptidase 1; ERMP1; ERMP1_HUMAN; Felix-ina; FXNA; KIAA1815; OTTHUMP00000215015; OTTHUMP00000215016; OTTHUMP00000215017.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 100kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FXNA:751-851/904
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Metallopeptidases are enzymes that catalyze the hydrolysis of peptide bonds and are essential to normal physiological processes, including tissue remodeling, reproduction and embryonic development. FXNA (felix-ina), also known as ERMP1 (endoplasmic reticulum metallopeptidase 1) or KIAA1815, is a 904 amino acid metallopeptidase that belongs to the peptidase M28 protein family. FXNA is a multi-pass membrane protein that localizes to the endoplasmic reticulum membrane. FXNA binds two zinc ions and, within the ovary, is essential to the organization of oocytes and somatic cells into discrete follicular structures. The gene that encodes FXNA maps to human chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype.
Function:
Within the ovary, required for the organization of somatic cells and oocytes into discrete follicular structures.
Subcellular Location:
Endoplasmic reticulum membrane.
Similarity:
Belongs to the peptidase M28 family.
SWISS:
Q7Z2K6
Gene ID:
79956
Database links:Entrez Gene: 79956Human
Omim: 611156Human
SwissProt: Q7Z2K6Human
Unigene: 591078Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.