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货号: bs-14589R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-14589R
- 英文名称
- EMR4
- 中文名称
- EMR4蛋白抗体
- 别 名
- EGF like module containing mucin like hormone receptor like 4; EGF TM7 receptor EMR4; EMR4P; EMR4_HUMAN; FIRE; G protein coupled receptor 127; G protein coupled receptor PGR16; GPR127; PGR16; Putative EGF like module containing mucin like hormone receptor like 4.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 信号转导 细胞粘附分子 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 49kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EMR4:331-440/457
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008]
Function:
EMR4 could mediate the cellular interaction between myeloid cells and B-cells.
Subunit:
Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit) (By similarity).
Subcellular Location:
Cell Membrane; multi pass membrane protein
Post-translational modifications:
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit (By similarity).
Similarity:
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 2 EGF-like domains.
Contains 1 GPS domain.
SWISS:
Q86SQ3
Gene ID:
326342
Database links:Entrez Gene: 326342Human
Omim: 612305Human
SwissProt: Q86SQ3Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.