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货号： bs-14536R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14536R
- 英文名称
- EIF2B2
- 中文名称
- EIF2B2蛋白抗体
- 别 名
- EI2BB_HUMAN; EIF 2Bbeta; EIF-2Bbeta; EIF2B; EIF2B GDP GTP exchange factor subunit beta; EIF2B2; EIF2B2; ; EIF2BB; Eukaryotic translation initiation factor 2B; Eukaryotic translation initiation factor 2B beta; Eukaryotic translation initiation factor 2B, subunit 2; Eukaryotic translation initiation factor 2B, subunit 2 beta; Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; S20I15; S20III15; Translation initiation factor eIF-2B subunit beta.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EIF2B2:1-100/351
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011]
Function:
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
Subunit:
Complex of five different subunits; alpha, beta, gamma, delta and epsilon.
DISEASE:
Leukodystrophy with vanishing white matter (VWM) [MIM:603896]: A leukodystrophy that occurs mainly in children. Neurological signs include progressive cerebellar ataxia, spasticity, inconstant optic atrophy and relatively preserved mental abilities. The disease is chronic-progressive with, in most individuals, additional episodes of rapid deterioration following febrile infections or minor head trauma. While childhood onset is the most common form of the disorder, some severe forms are apparent at birth. A severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba is called Cree leukoencephalopathy. Milder forms may not become evident until adolescence or adulthood. Some females with milder forms of the disease who survive to adolescence exhibit ovarian dysfunction. This variant of the disorder is called ovarioleukodystrophy. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the eIF-2B alpha/beta/delta subunits family.
SWISS:
P49770
Gene ID:
8892
Database links:Entrez Gene: 8892Human
Entrez Gene: 513958Cow
Entrez Gene: 217715Mouse
Entrez Gene: 84005Rat
Entrez Gene: 405839Zebrafish
Omim: 606454Human
SwissProt: Q5E9B4Cow
SwissProt: P49770Human
SwissProt: Q99LD9Mouse
SwissProt: Q28690Rabbit
SwissProt: Q62818Rat
Unigene: 409137Human
Unigene: 29041Mouse
Unigene: 5910Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.