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货号： bs-14514R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14514R
- 英文名称
- EFCAB6
- 中文名称
- EFCAB6蛋白抗体
- 别 名
- DJBP; CAP binding protein complex interacting protein 1; DJ1 binding protein; DJBP; EFCB6_HUMAN; EF hand calcium binding domain 6; FLJ23588.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 173kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EFCAB6:1401-1501/1501
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Function:
Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ1 antagonizes this inhibition by abrogation of this complex. Six named isoforms produced by alternative splicing.
Subunit:
Binds PARK7. Part of a ternary complex containing PARK7, EFCAB6/DJBP and AR.
Subcellular Location:
Nucleus.
Tissue Specificity:
Specifically expressed in the testis.
Similarity:
Contains 17 EF-hand domains.
SWISS:
Q5THR3
Gene ID:
64800
Database links:Entrez Gene: 64800Human
SwissProt: Q5THR3Human
Unigene: 658996Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.