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货号： bs-14496R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14496R
- 英文名称
- EBPL
- 中文名称
- EBPL蛋白抗体
- 别 名
- Delta8-delta7 sterol isomerase related protein; EBPL; EBPL_HUMAN; EBRP; Emopamil binding protein like; Emopamil binding related protein; Emopamil-binding protein-like.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EBPL:51-150/206
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
EBPL is expressed as a homodimer with high levels found in liver, lung and kidney. As a transmembrane protein embedded on the endoplasmic reticulum, EBPL may function as a cholestenol delta-isomerase. The gene encoding EBPL is found on human chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Function:
Does not possess sterol isomerase activity and does not bind sigma ligands.
Subunit:
Homodimer.
Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity:
Widely expressed with highest levels in liver, lung and kidney.
Similarity:
Belongs to the EBP family.
SWISS:
Q9BY08
Gene ID:
84650
Database links:Entrez Gene: 84650Human
SwissProt: Q9BY08Human
Unigene: 433278Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.