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货号： bs-18158R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18158R-Cy3
- 英文名称
- Anti-TNPO3/Cy3
- 中文名称
- Cy3标记的转运蛋白3抗体
- 别 名
- TNPO 3; Imp12; Importin 12; Importin-12; IPO12; MTR10A; TNPO 3; TNPO3; TNPO3_HUMAN; Transportin 3; Transportin SR; Transportin-3; Transportin-SR; TRN SR; TRN-SR; TRN-SR2; TRNSR.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 转录调节因子 脂蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 104kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TNPO3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
Function:
Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins SFRS1 and SFRS2, by recognizing phosphorylated RS domains.
Subunit:
Interacts with phosphorylated SFRS1 and SFRS2. Interacts with NUP62 and RBM4.
Subcellular Location:
Cytoplasm. Nucleus.
Database links:Entrez Gene: 23534Human
Entrez Gene: 320938Mouse
Omim: 610032Human
SwissProt: Q9Y5L0Human
SwissProt: Q6P2B1Mouse
Unigene: 193613Human
Unigene: 276381Mouse
Unigene: 304472Mouse
Unigene: 352219Mouse
Unigene: 424508Mouse
Unigene: 429470Mouse
Unigene: 439108Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.