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货号： bs-18053R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18053R-Cy3
- 英文名称
- Anti-HMGCLL1/Cy3
- 中文名称
- Cy3标记的HMGCLL1蛋白抗体
- 别 名
- 3 hydroxymethyl 3 methylglutaryl CoA lyase like protein 1; 3 hydroxymethyl 3 methylglutaryl Coenzyme A lyase like 1; Probable 3 hydroxymethyl 3 methylglutaryl CoA lyase 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HMGCLL1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein 1 (HMGCLL1) is a 370 amino acid protein that belongs to the HMG-CoA lyase family and is involved in the catabolism of branched amino acids, such as leucine and isoleucine. The gene encoding HMGCLL1 maps to human chromosome 6, which contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinsons disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6.
Function:
HMGCLL1 is involved in the catabolism of branched amino acids such as leucine.
Similarity:
Belongs to the HMG-CoA lyase family.
Database links:Entrez Gene: 54511Human
Entrez Gene: 208982Mouse
Entrez Gene: 367112Rat
SwissProt: Q8TB92Human
SwissProt: Q8JZS7Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.