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货号： bs-17884R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17884R-Cy3
- 英文名称
- Anti-MTMR12/Cy3
- 中文名称
- Cy3标记的肌微管素相关蛋白12抗体
- 别 名
- 3 PAP; 3 phosphatase adapter protein; 3 phosphatase adapter subunit; 3-PAP; 3-phosphatase adapter protein; 3PAP; KIAA1682; Mtmr12; MTMRC_HUMAN; Myotubularin related protein 12; Myotubularin-related protein 12; Phosphatidylinositol 3 phosphate 3 phosphatase adapter subunit; Phosphatidylinositol 3 phosphate associated protein; Phosphatidylinositol-3 phosphate 3-phosphatase adapter subunit; PIP3AP.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse, Rabbit, Sheep, Cat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 86kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MTMR12
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Function:
Catalytically inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.
Subcellular Location:
Cytoplasm. Localizes to punctate vesicles when associated with MTM1.
Tissue Specificity:
Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung.
Similarity:
Belongs to the protein-tyrosine phosphatase family.
Non-receptor class myotubularin subfamily.Contains 1 myotubularin
phosphatase domain.
Database links:Entrez Gene: 54545Human
Entrez Gene: 268783Mouse
Entrez Gene: 310155Rat
Entrez Gene: 569130Zebrafish
Omim: 606501Human
SwissProt: Q9C0I1Human
SwissProt: Q80TA6Mouse
SwissProt: Q5FVM6Rat
SwissProt: A2BGG1Zebrafish
Unigene: 481836Human
Unigene: 54460Mouse
Unigene: 214625Rat
Unigene: 87790Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.