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货号： bs-14429R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14429R
- 英文名称
- DSCAML1
- 中文名称
- 唐氏综合症细胞粘附分子2抗体
- 别 名
- Down syndrome cell adhesion molecule 2; Down syndrome cell adhesion molecule like 1; Down syndrome cell adhesion molecule like protein 1; Down syndrome cell adhesion molecule-like protein 1; DSCAM2; DSCAML1; DSCL1_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 发育生物学 神经生物学 细胞粘附分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 222kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DSCAML1:151-250/2053 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
DSCAML1 is a cell adhesion molecule that contains six Fibronectin type-III domains and ten Ig-like C2-type domains. DSCAML1 is involved in regulating isoneuronal self-avoidance, the tendency for sister arbors to avoid crossing each other and to spread out proportionately over an area. Isoneuronal self-avoidance is important for proper terminal branching (arborization). DSCAML1 also promotes heteroneuronal self-avoidance to maintain mosaic spacing between aII amacrine cells. DSCAML1 is expressed in liver, skeletal muscle, brain, kidney, pancreas and heart and exists as two isoforms produced by alternative splicing events.
Function:
Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Promotes both isoneuronal self-avoidance for creating an orderly neurite arborization in retinal rod bipolar cells and heteroneuronal self-avoidance to maintain mosaic spacing between AII amacrine cells.
Subcellular Location:
Cell membrane.
Tissue Specificity:
Detected in heart, liver, pancreas, skeletal muscle, kidney and in brain, in particular in the amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra, thalamus and subthalamus.
Similarity:
Contains 6 fibronectin type-III domains.
Contains 10 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
Q8TD84
Gene ID:
57453
Database links:Entrez Gene: 57453 Human
Entrez Gene: 114873 Mouse
Entrez Gene: 315615 Rat
Omim: 611782 Human
SwissProt: Q8TD84 Human
SwissProt: Q4VA61 Mouse
Unigene: 659513 Human
Unigene: 325499 Mouse
Unigene: 100124 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.