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货号： bs-16527R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16527R-Cy3
- 英文名称
- Anti-HSD17B14/Cy3
- 中文名称
- Cy3标记的17β羟类固醇脱氢酶14/17β-HSD14抗体
- 别 名
- 17 beta hydroxysteroid dehydrogenase 14; 17 beta hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; DHRS10; DHB14_HUMAN; Retinal short chain dehydrogenase/reductase 3; Retinal short chain dehydrogenase/reductase retSDR3; retSDR3; SDR3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 28kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HSD17B14
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Function:
HSD17B14 belongs to the short-chain dehydrogenases/reductases (SDR) family. It has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity and converts oestradiol to oestrone. The physiological substrate is not known. HSD17B14 acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro). It is highly expressed in brain, placenta, liver and kidney.
Subunit:
Homotetramer.
Subcellular Location:
Cytoplasmic
Tissue Specificity:
Highly expressed in brain, placenta, liver and kidney.
Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Database links:Entrez Gene: 51171Human
Omim: 612832Human
SwissProt: Q9BPX1Human
Unigene: 18788Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.