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货号： bs-14142R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14142R
- 英文名称
- CYLC2
- 中文名称
- CYLC2蛋白抗体
- 别 名
- CYL2; CYLC 2; Cylicin 2; Cylicin basic protein of sperm head cytoskeleton 2; Cylicin II; Cylicin2;Cylicin-2; MGC129591; Multiple band polypeptide II.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 发育生物学 干细胞 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CYLC2:21-120/348
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Cylicin-2 is a 348 amino acid protein encoded by the human gene CYLC2. Cylicin-1 is a type of a cytoskeletal protein which contains numerous Lys-Lys-Asp tripeptides accumulated in nine central repetitive units predicted to form a-helices. Cylicin-2, present in cow and human sperm heads, has the same prominent molecular characteristics as Cylicin-1, including a high content of charged amino acids, the abundance of Lys-Lys-Asp tripeptides and repetitive units of presumably a-helical configuration. Cylicin-2 is found in the acrosomal region of round spermatids and in the post-acrosomal region of late spermatids and spermatozoa, in agreement with the localization of Cylicin-1. Cylicin-2 is a novel Actin-binding protein, which probably plays a role in the Actin-related events that occur during spermiogenesis and the early events of fertilization.
Function:
CYCL2 (Cylicin II) is specifically expressed in testis and is part of the cytoskeletal calyx of mammalian sperm heads. Cylicin II may play a role in the morphogenesis of the sperm head and may be involved in spermatid differentiation.
Subcellular Location:
Cytoplasm, cytoskeleton, perinuclear theca, calyx. Note=Sperm head cytoskeletal structure.
Tissue Specificity:
Testis.
SWISS:
P08574
Gene ID:
1537
Database links:Entrez Gene: 1537Human
Entrez Gene: 1539Human
Omim: 604035Human
SwissProt: P08574Human
SwissProt: Q14093Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.