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货号： bs-14027R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14027R-Cy3
- 英文名称
- Anti-CPNE3/Cy3
- 中文名称
- Cy3标记的钙依赖膜结合蛋白Copine蛋白3抗体
- 别 名
- Copine 3; Copine III; Copine-3; Copine3; CopineIII; CPN3; CPNE 3; CPNE3; CPNE3_HUMAN; KIAA0636; PRO1071.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 结合蛋白 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CPNE3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Copine 3 is a member of the copine family of evolutionarily conserved, soluble, calcium-dependent, membrane-binding proteins. Members of the copine family are involved in signal transduction and membrane trafficking. Copine 3 is ubiquitously expressed and contains two N-terminal C2 domains and one C-terminal VWFA (von Willebrand factor A) domain, which is also referred to as the A domain or the core domain. As is characteristic of the copine family, copine 3 functions in membrane trafficking and is capable of binding phospholipids in a calcium-dependent manner. Differing from other members of the copine family, copine 3 may possess some intrinsic kinase activity. Copine 3 exists as a monomer in the cytosol and undergoes a conformational change upon binding to calcium.
Function:
May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.
Tissue Specificity:
Ubiquitous.
Post-translational modifications:
Phosphorylated on serine and threonine residues.
Similarity:
Belongs to the copine family.
Contains 2 C2 domains.
Contains 1 VWFA domain.
Database links:Entrez Gene: 8895Human
Entrez Gene: 615304Cow
Entrez Gene: 70568Mouse
Omim: 604207Human
SwissProt: O75131Human
SwissProt: Q8BT60Mouse
Unigene: 191219Human
Unigene: 38390Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.