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货号： bs-13961R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-13961R-Cy3
- 英文名称
- Anti-SLC44A4/Cy3
- 中文名称
- Cy3标记的胆碱转运体样蛋白4
- 别 名
- Solute carrier family 44, member 4;SLC44A4;CTL4;FLJ14491;NG22; CTL4_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 淋巴细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 79kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC44A4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Choline is an essential nutrient that is required for the synthesis of both acetylcholine, a neurotransmitter found in cholinergic nerve terminals, and phosphatidylcholine, a key component of cell membranes. Choline deficiencies are associated with defects in cell growth and have been implicated in disorders such as Alzheimer’s and Parkinson’s disease. The choline transporter-like protein family (CTL) are solute carriers that transport choline, a compound which is not able to permeate cells, across the cell membrane. CTL4, also known as SLC44A4 (Solute carrier family 44 member 4), is a multi-pass membrane protein which can fuse with Neu1, generating a CTL4-Neu1 transcript. This fusion is implicated in sialidosis, a disease characterized by improper lysosomal storage.
Subcellular Location:
Membrane; Multi-pass membrane protein (By similarity).
DISEASE:
Note=An interstitial deletion causing the fusion of exon 10 of CTL4 with the 3-UTR of NEU has been detected in two patients affected by sialidosis.
Similarity:
Belongs to the CTL (choline transporter-like) family.
Database links:
UniProtKB/Swiss-Prot: Q53GD3.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.