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货号： bs-10410R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-10410R
- 英文名称
- chemerin
- 中文名称
- 趋化素抗体
- 别 名
- Rarres2; TIG2; tazarotene induced gene 2; Retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; RAR-responsive protein TIG2; Chemerin.
- Specific References (3) | bs-10410R has been referenced in 3 publications.[IF=2.13] Krautbauer, Sabrina, et al. "Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver." Experimental and molecular pathology (2013). Mouse.PubMed:23906870[IF=5.52] Gonzalvo-Feo, Safiye, et al. "Endothelial Cell–Derived Chemerin Promotes Dendritic Cell Transmigration." The Journal of Immunology (2014): 1302028. Mouse.PubMed:24470498[IF=4.43] Akamata, Kaname, et al. "Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis." Rheumatology (2014): keu479. IHC-P ; Human.PubMed:25539827
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 心血管 信号转导 脂蛋白 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Pig, Cow, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from rabbi chemerin:101-163/163
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Chemerin, also known as retinoic acid receptor responder 2 (RARRES2) and tazarotene induced gene 2 (TIG2), is a chemoattractant protein for cells expressing G-protein-linked receptor chemokine-like receptor 1 (CMKLR1, ChemR23 or GPCR-DEZ). The protein is synthesized as a secreted precursor, prochemerin (18 kDa), which is poorly active. Upon proteolytic removal of the last six amino acids, prochemerin is converted into mature active chemerin (15-16 kDa) that acts as a strong and highly specific agonist of its receptor CMKLR1. Chemerin is a newly described adipokine with effects on adipocyte differnetiation and metabolism.
Subcellular Location:
Secreted (Potential).
Tissue Specificity:
Highly expressed in skin (basal and suprabasal layers of the epidermis, hair follicles and endothelial cells). Also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon.
SWISS:
Q99969
Gene ID:
5919
Database links:Entrez Gene: 5919 Human
Omim: 601973 Human
SwissProt: Q99969 Human
Unigene: 647064 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.