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货号： bs-13310R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-13310R
- 英文名称
- GCC1
- 中文名称
- 高尔基体卷曲螺旋蛋白1抗体
- 别 名
- GCC protein; GCC1P; GCC88; Golgi coiled coil 1; Golgi coiled coil protein 1; GRIP and coiled coil domain containing 1; Peripheral membrane Golgi protein; GCC1_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 细胞定位
- 细胞浆 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GCC1:401-500/775
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
GCC1 is a 775 amino acid cytoplasmic and peripheral membrane protein of the Golgi apparatus. Involved in maintenance of Golgi structure, GCC1 is essential for retrograde transport of cargo from the early endosomes to the trans-Golgi network. GCC1 contains one GRIP domain and is encoded by a gene that maps to human chromosome 7q32.1. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Function:
GCC1 is a peripheral membrane protein and is sensitive to brefeldin A. GCC1 contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport.
Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein.
Similarity:
Contains 1 GRIP domain.
SWISS:
Q96CN9
Gene ID:
79571
Database links:Entrez Gene: 79571 Human
Omim: 607418 Human
SwissProt: Q96CN9 Human
Unigene: 521168 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.