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货号： bs-13196R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-13196R
- 英文名称
- FPGS
- 中文名称
- 叶酸盐多谷氨酸合成酶抗体
- 别 名
- EC 6.3.2.17; FOLC; FOLC_HUMAN; Folylpoly gamma glutamate synthetase; Folylpoly-gamma-glutamate synthetase; Folylpolyglutamate synthase; Folylpolyglutamate synthase mitochondrial; FPGS; mitochondrial; OTTHUMP00000022201; OTTHUMP00000022202; Tetrahydrofolate synthase; Tetrahydrofolylpolyglutamate synthase.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FPGS/Folylpolyglutamate synthase:51-150/587
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq, Jul 2008].
Function:
Conversion of folates to polyglutamate derivatives. This allows tissues to concentrate folate at higher levels than in plasma.
Subunit:
Monomer.
Subcellular Location:
Mitochondrion. Cytoplasm.
Similarity:
Belongs to the folylpolyglutamate synthase family.
SWISS:
Q05932
Gene ID:
2356
Database links:Entrez Gene: 2356 Human
Omim: 136510 Human
SwissProt: Q05932 Human
Unigene: 335084 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.