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货号： bs-9089R-Cy3 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9089R-Cy3
- 英文名称
- Anti-FBXO27/Cy3
- 中文名称
- Cy3标记的FBXO27蛋白抗体
- 别 名
- F-box G-domain protein 5; F-box only protein 27; F-box protein 27; F-box protein FBG5; FBG5; Fbx27.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FBXO27
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin (CUL1), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.
Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with SKP1 and CUL1.
Tissue Specificity:
Predominantly expressed in brain, heart and kidney. Expressed at lower levels in liver and lung.
Similarity:
Contains 1 F-box domain.
Contains 1 FBA (F-box associated) domain.
Database links:Entrez Gene: 126433 Human
Entrez Gene: 233040 Mouse
Omim: 609099 Human
SwissProt: Q8NI29 Human
SwissProt: Q6DIA9 Mouse
Unigene: 187461 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.