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货号： bsm-51311M-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-51311M-FITC
- 英文名称
- Anti-RAB3A/FITC
- 中文名称
- FITC标记的小鼠抗Ras癌基因家族Rab3a单克隆抗体
- 别 名
- Rab 3A; RAB 3A member RAS oncogene family; Rab3a; RAB3A member RAS oncogene family; RAB3A_HUMAN; RAS associated protein RAB 3A; RAS associated protein RAB3A; Ras related protein Rab 3A; Ras related protein Rab3A; Ras-related protein Rab-3A.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 信号转导 G蛋白信号
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 5B7
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- Recombinant human RAB3A
- 亚 型
- IgG1,k
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RAB3A (RAB3A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB3A include Growth Hormone Deficiency, Isolated, Type Ii. Among its related pathways are Innate Immune System and Neurotransmitter Release Cycle. GO annotations related to this gene include GTP binding and protein C-terminus binding. An important paralog of this gene is RAB3C.
Function:
Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
Subunit:
Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A and RPH3AL. Interacts with the exocyst complex through SEC15. Binds SYTL4 and RIMS1. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3 (By similarity).
Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
Tissue Specificity:
Specifically expressed in brain.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
Database links:Entrez Gene: 5864 Human
Entrez Gene: 19339 Mouse
Entrez Gene: 25531 Rat
Omim: 179490 Human
SwissProt: P20336 Human
SwissProt: P63011 Mouse
SwissProt: P63012 Rat
Unigene: 27744 Human
Unigene: 5083 Mouse
Unigene: 44409 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.