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货号： bs-12946R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-12946R
- 英文名称
- CSRP2
- 中文名称
- 富含半胱氨酸蛋白2抗体
- 别 名
- CRP 2; CRP2; CSRP2; CSRP2_HUMAN; Cysteine and glycine rich protein 2; Cysteine and glycine-rich protein 2; Cysteine rich protein 2; Cysteine-rich protein 2; LIM domain only 5 smooth muscle; LIM domain only protein 5; LMO 5; LMO-5; LMO5; SmLIM; Smooth muscle cell LIM protein.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 发育生物学 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CSRP2:101-193/193
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
CRP2 is a 193 amino acid nuclear protein that belongs to the CRP family of LIM domain proteins. Highly expressed in smooth muscle of aorta, CRP2 is thought to have a role in embryonic vascular system development and is downregulated following cell injury or PDGF-B exposure. CRP2 contains two LIM zinc-binding domains and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Function:
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
Subunit:
Interacts with CSRP2BP. The LIM domain 1 is necessary and sufficient for this interaction. Interacts with GLRX3 (By similarity).
Subcellular Location:
Nucleus.
Tissue Specificity:
Highly expressed in the aorta, but not in heart and skeletal muscle.
Similarity:
Contains 2 LIM zinc-binding domains.
SWISS:
Q16527
Gene ID:
1466
Database links:Entrez Gene: 1466 Human
Entrez Gene: 13008 Mouse
Entrez Gene: 29317 Rat
Omim: 601871 Human
SwissProt: Q32LE9 Cow
SwissProt: Q16527 Human
SwissProt: P97314 Mouse
SwissProt: Q62908 Rat
Unigene: 530904 Human
Unigene: 2020 Mouse
Unigene: 94754 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.