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货号： bs-12045R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-12045R
- 英文名称
- Cyclin M3
- 中文名称
- 周期素M3抗体
- 别 名
- ACDP3; Ancient conserved domain containing protein 3; CNNM3; DKFZp434I1016; FLJ20018; Metal transporter CNNM3; CNNM3_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学 信号转导 细胞周期蛋白 通道蛋白 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 76kDa
- 细胞定位
- 细胞浆 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Cyclin M3:251-350/707
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.
Function:
Cyclin M3 is a probable metal transporter. There are three named isoforms.
Subcellular Location:
Integral to plasma membrane; Multi-pass membrane protein
Tissue Specificity:
Widely expressed. Expressed at higher level in heart and spleen.
Similarity:
Belongs to the ACDP family.
Contains 2 CBS domains.
Contains 1 DUF21 domain.
SWISS:
Q8NE01
Gene ID:
26505
Database links:Entrez Gene: 26505 Human
Entrez Gene: 94218 Mouse
Entrez Gene: 301345 Rat
Omim: 607804 Human
SwissProt: Q8NE01 Human
SwissProt: Q32NY4 Mouse
Unigene: 711617 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.