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货号： bs-23071R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-23071R-FITC
- 英文名称
- Anti-Hes5/FITC
- 中文名称
- FITC标记的发状分裂相关增强子-5抗体
- 别 名
- Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Hes5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008]
Function:
Transcriptional repressor of genes that require a bHLH protein for their transcription
Subunit:
Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Subcellular Location:
Nucleus.
Tissue Specificity:
Expressed in fetal heart and brain tumors.
Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 Orange domain.
Database links:Entrez Gene: 388585 Human
Entrez Gene: 15208 Mouse
Entrez Gene: 79225 Rat
SwissProt: Q5TA89 Human
SwissProt: P70120 Mouse
SwissProt: Q03062 Rat
Unigene: 57971 Human
Unigene: 137268 Mouse
Unigene: 22422 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.