产品中心
当前位置：首页>产品中心Anti-SLC19A1/FITC
货号： bs-19802R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19802R-FITC
- 英文名称
- Anti-SLC19A1/FITC
- 中文名称
- FITC标记的溶质载体家族蛋白19成员A1抗体
- 别 名
- CHMD; FLOT 1; FLOT1; Folate transporter 1; FOLT; IFC 1; IFC-1; IFC1; Intestinal folate carrier 1; Intestinal folate carrier; OTTHUMP00000115459; OTTHUMP00000115460; Placental folate transporter; Reduced folate carrier; Reduced folate carrier protein; REFC; RFC 1; RFC; RFC1; S19A1_HUMAN; SLC19A1; Solute carrier family 19 member 1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 转运蛋白 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 64kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC19A1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1) is a Protein Coding gene. Diseases associated with SLC19A1 include placental choriocarcinoma and thiamine-responsive megaloblastic anemia syndrome. Among its related pathways are Cell Cycle, Mitotic and Metabolism. GO annotations related to this gene include oxidoreductase activity and folic acid transporter activity. An important paralog of this gene is SLC19A2.
Function:
Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump.
Subcellular Location:
Membrane.
Tissue Specificity:
Placenta, liver, and to a much smaller extent, in lung.
Post-translational modifications:
Heavily glycosylated.
Similarity:
Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
Database links:Entrez Gene: 6573Human
Entrez Gene: 29723Rat
Omim: 600424Human
SwissProt: P41440Human
SwissProt: Q62866Rat
Unigene: 84190Human
Unigene: 9042Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.