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货号： bs-19632R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19632R-FITC
- 英文名称
- Anti-SENP2 /FITC
- 中文名称
- FITC标记的泛素样蛋白特异性蛋白酶2抗体
- 别 名
- Axam2; DKFZp762A2316; KIAA1331; Senp2;SERP2; SENP2_HUMAN; Sentrin specific protease 2; Sentrin-specific protease 2; Sentrin/SUMO specific protease SENP2; Sentrin/SUMO-specific protease SENP2; SMT3 specific isopeptidase 2; SMT3-specific isopeptidase 2; Smt3ip2; SUMO1/sentrin/SMT3 specific peptidase 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 泛素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 68kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SENP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]
Function:
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
Subcellular Location:
Nucleus > nuclear pore complex. Nucleus membrane. Cytoplasm. Shuttles between cytoplasm and nucleus.
Post-translational modifications:
Polyubiquitinated; which leads to proteasomal degradation.
Similarity:
Belongs to the peptidase C48 family.
Database links:Entrez Gene: 59343Human
Entrez Gene: 75826Mouse
Entrez Gene: 78973Rat
Omim: 608261Human
SwissProt: Q9HC62Human
SwissProt: Q91ZX6Mouse
SwissProt: Q9EQE1Rat
Unigene: 401388Human
Unigene: 297431Mouse
Unigene: 9367Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.