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货号： bs-18831R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18831R-FITC
- 英文名称
- Anti-RPS6KC1/FITC
- 中文名称
- FITC标记的p52核糖体蛋白S6激酶抗体
- 别 名
- p52 S6 kinase;52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1_HUMAN; Ribosomal protein S6 kinase 52kD polypeptide 1; Ribosomal protein S6 kinase 52kDa polypeptide 1; Ribosomal protein S6 kinase delta 1; Ribosomal protein S6 kinase delta-1; Ribosomal S6 kinase like protein with two PSK domains 118 kDa protein; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK 118; RPK118; RPS6KC1; S6K-delta-1; SPHK1 binding protein; SPHK1-binding protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 119kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RPS6KC1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
p52 S6 kinase, also known as RPS6KC1 (ribosomal protein S6 kinase, 52kDa, polypeptide 1) or RPK118, is a 1,066 amino acid member of the Ser/Thr kinase family that localizes to both the cytoplasm and the nucleus and contains one MIT domain, one PX domain and two protein kinase domains. Expressed at high levels in brain, placenta, heart, testis, kidney, liver and skeletal muscle, p52 S6 kinase catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.
Function:
May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell.
Subcellular Location:
Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures.
Tissue Specificity:
Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.
Similarity:
Belongs to the protein kinase superfamily.
Ser/Thr protein kinase family.
S6 kinase subfamily.
Contains 1 MIT domain.
Contains 2 protein kinase domains.
Contains 1 PX (phox homology) domain.
Database links:Entrez Gene: 26750Human
Entrez Gene: 320119Mouse
GenBank: NP_001129610.1Human
GenBank: NP_036556.2Human
SwissProt: Q96S38Human
SwissProt: Q8BLK9Mouse
Unigene: 591416Human
Unigene: 220912Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.