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货号: bs-12196R 基本售价: 1380.0 元 规格: 100ul
- 规格:100ul
- 价格:1380.00元
- 规格:200ul
- 价格:2200.00元
产品信息
- 产品编号
- bs-12196R
- 英文名称
- HOXC4
- 中文名称
- 同源盒蛋白C4抗体
- 别 名
- CP 19; CP19; Homeo box 3E; Homeo box C4; Homeo box protein HoxC4; Homeobox 3E; Homeobox C4; Homeobox protein CP19; Homeobox protein Hox C4; Homeobox protein Hox-3E; Homeobox protein Hox-C4; Homeobox protein HoxC4; Homeobox3E; HomeoboxC4; HOX 3; Hox 3E; HOX C4; HOX3; Hox3E; HOXC 4; Hoxc4; HXC4_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 发育生物学 信号转导 转录调节因子 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Zebrafish, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HOXC4:181-264/264
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Homeobox (HOX) genes, which share a highly conserved 183-bp sequence, encode proteins capable of binding to specific DNA sequences and functioning as transcription factors. During embryogenesis, HOX genes play a critical role in the spatial and temporal differentiation of cells. HoxC4, a sequence-specific transcription factor, belongs to the Antp HOX family and localizes to the nucleus. It functions as a part of a developmental regulatory system, providing cells with specific positional identities on the anterior-posterior axis. HoxC4 expression levels increase with differentiation of lymphoid cells, suggesting its role in the molecular regulation of hematopoiesis. HoxC4 is also expressed in differentiated keratinocytes.
Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Antp homeobox family. Deformed subfamily.
Contains 1 homeobox DNA-binding domain.
SWISS:
P09017
Gene ID:
3221
Database links:Entrez Gene: 613740 Cow
Entrez Gene: 3221 Human
Entrez Gene: 15423 Mouse
Entrez Gene: 24459 Rat
Entrez Gene: 30345 Zebrafish
Omim: 142974 Human
SwissProt: P09017 Human
SwissProt: Q08624 Mouse
SwissProt: P18865 Rat
SwissProt: Q9PWM3 Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.