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货号： bs-18603R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18603R-FITC
- 英文名称
- Anti-MACROD2/C20orf133/FITC
- 中文名称
- FITC标记的20号染色体开放阅读框133抗体
- 别 名
- C20orf133; MACD2_HUMAN; MACRO domain containing 2; MACRO domain-containing protein 2; macrod2; O-acetyl-ADP-ribose deacetylase MACROD2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 50kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MACROD2/C20orf133
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MACROD2 (MACRO Domain Containing 2) is a Protein Coding gene. Diseases associated with MACROD2 include autism spectrum disorder and pervasive developmental disorder. GO annotations related to this gene include hydrolase activity, acting on glycosyl bonds and deacetylase activity. An important paralog of this gene is MACROD1.
Function:
Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.
Subunit:
Interacts with ADP-ribosylated PARP1.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 Macro domain.
Database links:Entrez Gene: 140733Human
Entrez Gene: 72899Mouse
SwissProt: A1Z1Q3Human
SwissProt: Q3UYG8Mouse
Unigene: 661576Human
Unigene: 229466Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.