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货号： bs-18504R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18504R-FITC
- 英文名称
- Anti-ZNF289/ARFGAP2/FITC
- 中文名称
- FITC标记的锌指蛋白289抗体
- 别 名
- ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; ARFGAP2; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF 289.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 57kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF289/ARFGAP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ZNF289 functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles.
Function:
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Subunit:
Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.
Subcellular Location:
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Similarity:
Contains 1 Arf-GAP domain.
Database links:Entrez Gene: 84364Human
Entrez Gene: 505438Cow
Entrez Gene: 77038Mouse
Entrez Gene: 362162Rat
Omim: 606908Human
SwissProt: A1L520Cow
SwissProt: Q8N6H7Human
SwissProt: Q99K28Mouse
SwissProt: Q3MID3Rat
Unigene: 436204Human
Unigene: 43636Mouse
Unigene: 3707Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.