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货号： bs-18364R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18364R-FITC
- 英文名称
- Anti-LRP3/FITC
- 中文名称
- FITC标记的低密度脂蛋白受体相关蛋白3抗体
- 别 名
- 105 kDa low-density lipoprotein receptor-related protein; hLRp105; Low density lipoprotein receptor related protein 3; Low-density lipoprotein receptor-related protein 3; LRP-3; Lrp3; LRP3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 细胞膜受体 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 79kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LRP3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Low-density lipoprotein receptor-related protein 3 (LRP3) is a 770 amino acid protein that contains two CUB domains and four LDL-receptor class A domains. LRP3 is widely expressed with highest expression in skeletal muscle and ovary and lowest expression in testis, colon and leukocytes. LRP3 is potentially a membrane receptor involved in the internalization of lipophilic molecules and/or signal transduction.
Function:
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.
Subcellular Location:
Membrane. Membrane > coated pit.Target information above from: UniProt accession O75074 The UniProt ConsortiumThe Universal Protein Resource (UniProt) in 2010Nucleic Acids Res. 38:D142-D148 (2010) .
Tissue Specificity:
Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.
Similarity:
Belongs to the LDLR family.
Contains 2 CUB domains.
Contains 4 LDL-receptor class A domains.
Database links:Entrez Gene: 4037Human
Entrez Gene: 435965Mouse
Entrez Gene: 89787Rat
Omim: 603159Human
SwissProt: O75074Human
SwissProt: O88204Rat
Unigene: 515340Human
Unigene: 273631Mouse
Unigene: 145216Rat
Unigene: 87059Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.