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货号： bs-17151R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17151R-FITC
- 英文名称
- Anti-STX17/FITC
- 中文名称
- FITC标记的突触17抗体
- 别 名
- FLJ20651; MGC102796; MGC126613; MGC126615; Stx17; STX17_HUMAN; Syntaxin 17; Syntaxin-17.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human STX17
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 17, also known as STX17, is a 302 amino acid single-pass type IV membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the syntaxin family. Thought to localize to the endoplasmic reticulum, Syntaxin 17 plays a role in vesicle trafficking to lysosomes and may be involved in processes related to cell division. The gene encoding Syntaxin 17 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Function:
Implicated in vesicle trafficking to lysosomes. Could be involved in processes related to cell division.
Subcellular Location:
Membrane. Appears to be associated with a membrane compartment, perhaps a subset of the ER such as exit or entrance sites.
Similarity:
Belongs to the syntaxin family.
Contains 1 t-SNARE coiled-coil homology domain.
Database links:Entrez Gene: 55014Human
Omim: 604204Human
SwissProt: P56962 Human
Unigene: 704031Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.