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货号： bs-16701R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16701R-FITC
- 英文名称
- Anti-IRF2BP2/FITC
- 中文名称
- FITC标记的干扰素调节因子2结合蛋白2抗体
- 别 名
- I2BP2_HUMAN; Interferon regulatory factor 2 binding protein 2; Interferon regulatory factor 2-binding protein 2; IRF-2-binding protein 2; IRF-2BP2; IRF2 binding protein 2; IRF2BP2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 61kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IRF2BP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Function:
Acts as a transcriptional repressor. Acts as a transcriptional corepressor in a IRF2-dependent manner. This repression is not mediated at least in part by histone deacetylase activities.
Subunit:
Interacts with IRF2. Part of a corepressor complex containing IRF2 and IRF2BP1. Interacts with VGLL4.
Subcellular Location:
Nucleus.
Post-translational modifications:
Phosphorylation at Ser-360 is required for nuclear targeting.
Similarity:
Belongs to the IRF2BP family.
Database links:Entrez Gene: 359948Human
Entrez Gene: 270110Mouse
Omim: 615332Human
SwissProt: Q7Z5L9Human
SwissProt: E9Q1P8Mouse
Unigene: 350268Human
Unigene: 491125Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.