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货号： bs-16566R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16566R-FITC
- 英文名称
- Anti-TRAM2/FITC
- 中文名称
- FITC标记的相关易位膜蛋白2抗体
- 别 名
- C330003D03Rik; KIAA0057; MGC25725; OTTHUMP00000016607; TRAM like protein; Tram2; TRAM2_HUMAN; Translocating chain associating membrane protein 2; Translocating chain-associated membrane protein 2; Translocation associated membrane protein 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 跨膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TRAM2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004]
Function:
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Subcellular Location:
Membrane.
Similarity:
Belongs to the TRAM family.
Contains 1 TLC (TRAM/LAG1/CLN8) domain.
Database links:Entrez Gene: 9697Human
Entrez Gene: 617287Cow
Entrez Gene: 474936Dog
Entrez Gene: 100730382 Guinea pig
Entrez Gene: 100069225Horse
Entrez Gene: 170829Mouse
Entrez Gene: 100157796Pig
Entrez Gene: 301296Rat
Entrez Gene: 406344Zebrafish
Omim: 608485Human
SwissProt: Q15035Human
SwissProt: Q924Z5Mouse
Unigene: 520182Human
Unigene: 185680Mouse
Unigene: 273241Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.