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货号： bs-11638R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-11638R
- 英文名称
- LZIC
- 中文名称
- LZIC蛋白抗体
- 别 名
- Leucine zipper and CTNNBIP1 domain containing protein; Leucine zipper and ICAT homologous domain containing protein; leucine zipper domain and ICAT homologous domain containing; LZIC antibodyprotein LZIC; LZIC_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 21kDa
- 细胞定位
- 细胞核 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LZIC:31-130/190
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
LZIC is a 190 amino acid protein that belongs to the CTNNBIP1 family. Ubiquitously expressed, LZIC is found at highest levels in kidney and is upregulated in a few gastric carcinomas. The gene encoding LZIC maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Function:
LZIC belongs to the CTNNBIP1 family. It is ubiquitously expressed with highest levels in kidney. LZIC is up-regulated in several cases of gastric cancers.
Subunit:
Does not interact with CTNNB1
Tissue Specificity:
Ubiquitously expressed, with highest levels in kidney. Up-regulated in several cases of gastric cancers.
Similarity:
Belongs to the CTNNBIP1 family.
SWISS:
Q8WZA0
Gene ID:
84328
Database links:Entrez Gene: 419445 Chicken
Entrez Gene: 84328 Human
Entrez Gene: 69151 Mouse
Entrez Gene: 366507 Rat
Entrez Gene: 550045 Xenopus tropicalis
Entrez Gene: 436871 Zebrafish
Omim: 610458 Human
SwissProt: Q5ZKW2 Chicken
SwissProt: Q8WZA0 Human
SwissProt: Q8K3C3 Mouse
SwissProt: Q5PQN7 Rat
SwissProt: Q28D79 Xenopus tropicalis
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.