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货号： bs-2623R 基本售价： 380.0 元 规格： 20ul
- 规格：20ul
- 价格：380.00元
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-2623R
- 英文名称
- IL22
- 中文名称
- 白介素-22抗体
- 别 名
- Interleukin-22; Il22; IL-22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL23; zcyto18.
- Specific References (3) | bs-2623R has been referenced in 3 publications.[IF=2.09] Huang, Yong-Hong, et al. "Th22 cell accumulation is associated with colorectal cancer development."World Journal of Gastroenterology IHC-P ;PubMed:25892871[IF=1.42] Karaboga, İhsan, Selim Demirtas, and Turan Karaca. "Investigation of the relationship between the Th17/IL-23 pathway and innate-adaptive immune system in TNBS-induced colitis in rats." Iranian Journal of Basic Medical Sciences 20.8 (2017): 870-879. WB ; Rat.PubMed:0[IF=0.00] Zhang, Yan, and Mikhail G. Kolonin. "Cytokine signaling regulating adipose stromal cell trafficking." Adipocyte 5.4 (2016): 369-374. IHC-P ; Mouse.PubMed:27994950
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /test IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17kDa
- 细胞定位
- 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IL-22:35-179/179
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].
Function:
Cytokine that contributes to the inflammatory response in vivo.
Subcellular Location:
Secreted.
Similarity:
Belongs to the IL-10 family.
SWISS:
Q9GZX6
Gene ID:
50616
Database links:Entrez Gene: 50616 Human
Entrez Gene: 50929 Mouse
Entrez Gene: 500836 Rat
Omim: 605330 Human
SwissProt: Q9GZX6 Human
SwissProt: Q9JJY9 Mouse
Unigene: 287369 Human
Unigene: 103585 Mouse
Unigene: 195879 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
IL-22是白介素-10家族的成员,主要是由激活的T 淋巴细胞产生的一类重要的细胞因子,除了在Th17细胞中高表达之外，在NK和NKT等细胞中也有表达,在组织损伤修复以及牛皮癣、肝炎、肺炎、肠炎等慢性炎症中发挥重要作用.IL-22是继IL-6和IL-10之后又一个参与炎症反应和代谢调控的细胞因子，IL-22有可能成为干预脂肪肝发生发展的新方法。
- 产品图片
Sample:
A549(Human) Cell Lysate at 30 ug
Primary: Anti-IL22 (bs-2623R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 17 kD
Observed band size: 19 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IL22) Polyclonal Antibody, Unconjugated (bs-2623R) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody (sp-0023) for 20 minutes and DAB staining.
Blank control(blue): Mouse liver cells(fixed with 2% paraformaldehyde (10 min) , then permeabilized with 90% ice-cold methanol for 30 min on ice).
Primary Antibody: Rabbit Anti-IL22 antibody(bs-2623R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA;
Isotype Control Antibody: Rabbit IgG (orange) ,used under the same conditions.
Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA.