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货号： bs-14063R-FITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14063R-FITC
- 英文名称
- Anti-CRLS1/FITC
- 中文名称
- FITC标记的心磷脂合成酶1抗体
- 别 名
- 0610009I22Rik; 4930557M15Rik; 5730490M08; C20orf155; Cardiolipin synthase 1; Cardiolipin synthase; CLS; CLS1; CRLS1; CRLS1_HUMAN; dJ967N21.6; GCD10; OTTMUSP00000016677; Protein GCD10 homolog; RGD1311037; RP23-77H16.4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 细胞生物 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CRLS1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cardiolipin synthetase is a mitochondrial protein that belongs to the CDP-alcohol phosphatidyltransferase class-I family. CLS1 is a multi-pass membrane protein localized to the inner membrane of mitochondria. CLS1 is responsible for the catalyzing the reversible transfer of a phosphatidyl group from one phosphatidyl glycerol molecule to another. This process results in the formation of cardiolipin (CL, or diphosphatidyl glycerol) and glycerol. Diphosphatidyl glycerol is a major component of the mitochondrial membrane and constitutes roughly 20% of total mitochondrial lipids. Having four fatty acid tails rather than the usual two, CL is a double phospholipid that is synthesized in the mitochondrion itself. Defects in the CRLS1 gene are likely to effect metabolism, sustained production of ATP and could contribute to diseases such as Barth syndrome.
Function:
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Subcellular Location:
Mitochondrion inner membrane.
Tissue Specificity:
Highly expressed in tissues such as heart, skeletal muscle and liver.
Similarity:
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
Database links:Entrez Gene: 54675Human
Omim: 608188Human
SwissProt: Q9UJA2Human
Unigene: 224764Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.